Blogs and News
Discover our latest news and blog articles, dedicated to demystifying drug development, medicine, clinical research, and ethics.
How Artificial Intelligence Can Support Your Clinical Trial
Artificial intelligence (AI) promises efficiency, accuracy, and cost savings, but what can it actually deliver when it comes to clinical trials? Whether you’re in the design process of your clinical trial, working on regulatory submissions, recruiting participants, or collecting and analyzing data, there may be AI tools to help.
3 reasons why choosing a smaller CRO can boost your clinical trial
If you’re looking for the right CRO for your clinical trial, you’re likely considering many factors, including expertise, prior success, budget… but what’s size got to do with it? More than you might think. In this blog post, we look at the benefits of partnering with a smaller CRO.
3 Ways to make decentralization support patient centricity
Used in the right way, decentralization can help put patients at the heart of a clinical trial. But if a fully decentralized or hybrid trial is designed and implemented without considering participants’ perspectives, it can result in gaps in data, low participant retention and delays.
How Regulation and Technology Impacted Clinical Research in 2023
This has been a year of change in the clinical trials landscape, with developments in regulation and the evolution of technology driving the move toward more patient centricity. Here we look at some of the highlights.
Take a peek behind the scenes: how Siron Clinical works with clients
Choosing a partner to support your clinical trial is a big decision, and understanding what your collaboration might look like can help. After more than two decades of working with a multitude of clients, Siron Clinical has perfected the process from RFP and trial...
Five tips for keeping up-to-date with the latest in clinical trials
In the fast-moving field of clinical trials, it can be challenging to keep up-to-date with the latest news, views, and changes. But with new regulation frequently appearing around the world and technological innovation changing the face of clinical research, it’s more...
Preparation, quality and the local touch: Siron Clinical’s experience with the CTIS
Now nearing the end of their second year in use, the EU’s Clinical Trial Regulation and its associated Clinical Trials Information System (CTIS) have meant some big changes for sponsors and others involved in designing, getting approval for, and running clinical...
How small biotech can overcome clinical trial hurdles
Small biotech companies are responsible for a significant proportion of newly approved medicines, especially for rare diseases. But with limited resources, budget constraints and a lean structure, they face many challenges before they can help patients. Here we look...
Quality assurance – why it’s important and how to do it
Quality assurance is a critical element of a clinical trial, as it ensures the safety of the participants, as well as the reliability and integrity of the documentation and data, and therefore the validity of your results. But what does it entail, when should it happen, and how can you get it right? We share our insights.
Recruitment, decentralization and transparency: a round-up of the latest clinical trial news
Discover 2023 trends in recruitment decentralization for clinical trials, including advancements, challenges, and transparency initiatives.
Four factors to consider for your cardiovascular clinical trial
Cardiovascular clinical trials are essential in developing interventions like treatments and medical devices for a wide range of cardiovascular diseases. The sheer size and complexity of cardiovascular trials is just one of the factors that make this therapeutic area...
Patient recruitment – how to get (and keep) participants
People are at the core of every clinical trial. Patient recruitment can be one of the most challenging aspects of setting up a trial.
What to do with negative results clinical research – and why they don’t equal failure
It can be disappointing if your trial generates negative results; you may feel it has been a waste of time and resources. But negative results do not necessarily mean failure.
Medical device clinical trials can be challenging – here’s what to expect
Medical devices are vital for diagnosing, treating and monitoring diseases, saving lives and keeping us alive. There are about 2 million medical devices on the market today, in more than 7,000 categories. Each of them underwent a journey from innovation through clinical trials to the market. Here we look at medical devices, the challenges you can face with a trial and how to overcome them.
How an eTMF can improve your clinical trial
When you’re running a clinical trial, you need to make sure that your records, from protocols to results, are compliant, organized and managed so that they’re always ready for inspection. You can do this by effectively managing your trial master file (TMF) – a crucial element of a successful trial.
Four clinical trial trends to watch in 2023
In 2022, the clinical trials industry adjusted to post-pandemic reality, embracing new innovations that emerged from COVID-19. We expect many of these to continue: here we share four trends Siron Clinical will be watching in 2023 and beyond.
3 Tips for Running a Successful Oncology Trial
Cancer is a leading cause of death globally, but the more we understand about this complex group of diseases, the more opportunities we have to target it with new therapies. Running an oncology clinical trial can be challenging; here are three tips to help you succeed.
Why patients must remain central as clinical trial tech develops
The latest trends in clinical trials, like decentralization and AI, can help make a trial more efficient, effective and successful. But what if the patients at the center of the trial don’t like the new approaches?
Point-of-care clinical trials: the right approach for your research?
What if a clinical trial were integrated seamlessly into patient care, so each patient could get maximum benefit from the treatment on trial, while saving time and money? Point-of-care trials bring clinical research into everyday healthcare, and they have both advantages and challenges.
Pediatric Rare Disease Clinical Trials
There are many challenges to overcome if pediatric rare disease treatments are being tested, those challenges can be significantly greater.
How to train a clinical trial team (from a distance)
Before a clinical trial can start, everyone on the team needs to understand the research and their own role in it. Good training can support a successful result and going virtual can do it faster and more cost-effectively. Here are five tips.
Why representation is important in clinical trials
Discover why representation in clinical trials is crucial for accurate results and social justice in medical research.
Meet Ingrid Meine – Siron Clinical’s new Clinical Trial Manager
At Siron Clinical, people are our biggest strength. Here we meet Ingrid Meine, who joined the Siron Clinical team as Clinical Trial Manager.
Five Ways Decentralization Can Help Your Trial Succeed
The pandemic accelerated innovation around clinical trial decentralization, but remote approaches are here to stay. Here are five ways decentralization can help you succeed with your clinical trial.
Site Initiation Visits: Starting Your Trial On Track
To get the best start with a clinical trial, we carry out a site initiation visit (SIV). In this post, we look at what that entails and how we ensure it sets the trial off in a positive direction.
Modernizing Clinical Trials: Three Innovative Trial Designs From The FDA
There are many different types of clinical trial design, but most of the approaches we take to clinical research have been around for many years. Innovation in trial design could help improve outcomes and efficiency – and the FDA has shared some examples.
The EU’s move to better clinical trials that address patients’ needs – what you need to know
Clinical trials in the EU are changing in 2022 – the new EU Clinical Trials Regulation comes into force, backed by the Clinical Trials Information System (CTIS) and driven by an initiative to transform clinical trials. Here is a round-up of what it means for running a clinical trial in the EU.
Clinical Trial Support – 5 Reasons Why You Don’t Have To Do Everything Yourself
Clinical trials are complex, which means they involve a lot of work and require a range of skills and experience. It can be daunting when you start planning a clinical trial – how will you manage everything that’s needed, especially if you have a small team?
120 Clinical Trials In 20 Years: Discover Siron Clinical’s Expertise
One of the key drivers of our success as a CRO is our extensive experience with clinical trials across phase I and II trials, and in therapeutic areas including dermatology, oncology, pediatric and orphan indications.
How Clinical Trial Data Is Used – And Why It’s Important To Publish
How are the results of clinical trials applied? A clinical trial can generate a huge amount of data. Collecting, storing and managing that data is challenging, especially for large, complex, multi-site and multinational trials.
A Phase II Clinical Trial, Step By Step
Your drug has passed through the phase I clinical trial and you’ve selected and contacted the sites you want to work with. Now it’s time to get your trial up and running in the EU. What do you do? Let’s walk through the process step by step.
FDA, IRB, EMA… What Role Do Agencies Play In Clinical Trials?
At first glance, it’s abbreviation soup – EMA, FDA, NIHR, OHRP, IRB – but this collection of organizations is responsible for making sure clinical trials are run properly, to protect patients and develop medicines that are safe and effective.
What Is a CRO And How Can They Help You?
A clinical trial involves complex overlapping processes, many of which require specialized expertise and experience. So how can you run a clinical trial successfully if you don’t have the expertise in-house? That’s where a CRO comes in.
Experience Matters
As an international contract research organization (CRO), we offer unparalleled knowledge, support, guidance, and experienced clinical research professionals to the biotechnology, life science, and medical device industries. We are committed to leading the development of new and advanced treatments by offering a range of CRO clinical trial services, from Customizable FSP to full-service.