Our Therapeutic Expertise

At Siron Clinical, we’re proud of our expertise in tackling complex clinical trials. Our history over the past 20 years shows a breadth of expertise across a wide variety of indications. Not only are we trusted industry experts within clinical trials for orphan diseases, pediatrics, and medical devices, but we have deep experience in other therapeutic areas.

Dive Deeper Into Our Experience

Orphan Indications

Since our beginning, we have been continuously involved in clinical studies with rare diseases. We’ve come across many implementation challenges for rare disease clinical trials – and this experience means that we’re equipped to tackle your rare disease trial challenges.

Our orphan indication experience includes:

  • Pulmonary Hypertension
  • Chronic Thromboembolic Pulmonary Hypertension
  • Enzyme replacement therapy
  • Primary Biliary Cirrhosis
  • Primary Sclerosing Cholangitis
  • Familial Adenomatous Polyposis
  • Alpha-1 Antitrypsin Deficiency
  • Peanut allergy

Pediatric Studies

We know that pediatric trials are different – but our experience has shown us where these trials differ from regular clinical trials.  We know we can help you solve your challenges.

Our pediatric experience includes:

  • Pediatric Pulmonary Arterial Hypertension
  • Biliary Atresia
  • Peanut allergy

Cardiovascular Studies

With our vast experience, we have built a network that you can benefit from in both interventional and device studies.

Our cardiovascular interventional experience includes:

  • Hypertension
  • Unstable Angina
  • Myocardial Infarction
  • Left Ventricular Heart Failure
  • Pulmonary Hypertension
  • Coronary Artery Bypass Graft Surgery
  • Catecholamine Resistant Hypotension

Our cardiovascular devices experience includes:

  • Drug eluting stent
  • Renal ablation
  • Abdominal Aortic Aneurism
  • Aortic valve replacement (TAVI)
  • Atrioventricular Valved Stent

Oncology Studies

Our 20 years of experience within oncology trials has equipped us with a deep understanding of how to navigate the complexities inherent in such trials.  We’d welcome the opportunity to share this knowledge with you.

 Our oncology experience includes:

  • Metastatic Colorectal cancer
  • Advanced solid tumors
  • Non-Hodgkin Lymphoma
  • Breast, Ovarian, Pancreatic, Prostate, Colorectal, NSCLC, SCLC
  • Familial Adenomatous Polyposis
  • Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
  • Phase I dose escalating study in adult patients with advanced/metastatic solid tumors
  • Systemic B-cell lymphoma
  • Mucosa-associated lymphoid tissue (MALT) Lymphoma
  • Metastatic Castration-Resistant Prostate Cancer (mCRPC)
  • Benign Prostate Hypertrophy

Dermatology Studies

Our work in early phase dermatology means that we can help startups move forward, leading them through the complex clinical trial process.

Our dermatology experience includes:

  • Cutaneous warts
  • Atopic dermatitis
  • T-cell lymphoma
  • Solid Tumors
  • Actinic Keratosis (ICVT)
  • Usual type vulvar intraepithelial neoplasia
  • Facial seborrheic dermatitis
  • Psoriasis

Phase 1 Studies

Early phase, phase 1 and proof of concept studies need different approaches to clinical monitoring. Our experience shows that we can manage this.

Our phase 1 experience includes:

  • Phase I SD/MD PK/PD healthy volunteer studies
  • Phase I SAD/MAD PK/PD studies
  • Immunopharmacology

Other Indications

Our experience with complex clinical trials in other disease areas gives us a breadth of expertise.   We’re ready to tackle your clinical trial challenges.

  • Graft versus Host Disease, stem cell
  • Relapsing Remitting Multiple Sclerosis
  • Idiopathic Pulmonary Fibrosis
  • Acute Kidney Injury
  • Aneurismal Subarachnoidal Bleeding
  • Scleroderma
  • Portal Hypertension
  • Systemic Sclerosis
  • HPV-induced genital lesions
  • Septic Shock

Experience Matters

We offer unparalleled knowledge, support, guidance, and extremely experienced clinical research professionals to the biotechnology, life science, and medical device industries. We are committed to leading the development of new and advanced treatments.

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